I don't often watch "House", and I missed last night's episode, but I think it's one I would have watched. The episode was titled "The Softer Side", and it featured House treating a teenager diagnosed with genetic mosaicism. I'd heard of this before, but I didn't think it effected humans. A deeper reading of the synopsis describes the teen as having both male and female characteristics. Hmm... IMDb says the episode is set to air on the USA Network Friday, March 6. Set your DVR, or Tivo or whatever.
If anyone's already seen it, I'd appreciate their take on it, House is a cranky fellow, but the medicine on the show is usually handled in a realistic manner, from what I remember.